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Drug absorption and interactions: Delayed gastric emptying can theoretically affect the absorption kinetics of orally administered medications, particularly those with narrow therapeutic windows or requiring rapid onset

These questionnaires were completed at baseline and then weekly for the 4 wks of dosing

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Notably, while the increase in amniotic fluid CSE levels did not reach statistical significance, maternal serum CSE levels were significantly higher in Down syndrome cases compared to controls, with an approximately twofold increase

Additionally, IGF-1 levels were reported to rise by about 28%, hinting at an improved functionality of the growth hormone-IGF-1 axis

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